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Magnus von Knebel Doeberitz Selected Research

Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)

10/2021Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
1/2021Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
1/2021Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report.
1/2020Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome.
1/2019The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect.
1/2019High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer.
1/2018Three molecular pathways model colorectal carcinogenesis in Lynch syndrome.
10/2016CTNNB1-mutant colorectal carcinomas with immediate invasive growth: a model of interval cancers in Lynch syndrome.
2/2016Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.
6/2013Towards a vaccine to prevent cancer in Lynch syndrome patients.
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Magnus von Knebel Doeberitz Research Topics

Disease

79Neoplasms (Cancer)
01/2022 - 06/2002
25Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 04/2003
17Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)
10/2021 - 09/2006
14Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2020 - 11/2002
13Uterine Cervical Dysplasia
01/2016 - 11/2002
12Carcinoma (Carcinomatosis)
06/2012 - 12/2002
11Microsatellite Instability
07/2020 - 01/2004
10Carcinogenesis
01/2021 - 09/2003
7Papillomavirus Infections
01/2020 - 10/2010
6Turcot syndrome
10/2021 - 04/2007
6Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2019 - 05/2004
6Neoplasm Metastasis (Metastasis)
12/2016 - 02/2005
5Adenocarcinoma
01/2019 - 09/2003
4Squamous Cell Carcinoma of Head and Neck
01/2021 - 04/2015
3Endometrial Neoplasms (Endometrial Cancer)
01/2021 - 01/2004
3Pancreatic Neoplasms (Pancreatic Cancer)
12/2016 - 08/2002
3Adenoma (Adenomas)
06/2012 - 07/2007
3Infections
07/2007 - 06/2002
3Colonic Neoplasms (Colon Cancer)
09/2005 - 04/2004
2Anus Neoplasms (Anal Cancer)
11/2021 - 12/2014
2Vulvar Neoplasms (Vulvar Cancer)
01/2019 - 07/2013
2Atypical Squamous Cells of the Cervix
10/2012 - 02/2007
2Residual Neoplasm
07/2007 - 02/2002
1Genetic Anticipation
01/2019
1Cholangiocarcinoma
01/2019
1Stomach Neoplasms (Stomach Cancer)
01/2019
1Chronic Pancreatitis
12/2016
1Branchioma (Branchial Cleft Cysts)
04/2015
1Carcinoma in Situ
01/2012
1Chromosomal Instability (Chromosome Stability)
09/2010
1Wilms Tumor (Wilm's Tumor)
01/2010

Drug/Important Bio-Agent (IBA)

25DNA (Deoxyribonucleic Acid)IBA
11/2021 - 09/2003
19Proteins (Proteins, Gene)FDA Link
04/2021 - 09/2003
19Cyclin-Dependent Kinase Inhibitor p16IBA
05/2016 - 11/2002
15Biomarkers (Surrogate Marker)IBA
01/2019 - 11/2002
14Peptides (Polypeptides)IBA
10/2021 - 09/2003
13Calcibiotic Root Canal SealerIBA
01/2022 - 07/2007
11AntigensIBA
05/2016 - 09/2003
9VaccinesIBA
10/2021 - 12/2006
5Immune Checkpoint InhibitorsIBA
01/2021 - 01/2018
4ParaffinIBA
01/2022 - 08/2004
4Biological ProductsIBA
06/2021 - 01/2006
4Histocompatibility Antigens Class IIBA
01/2018 - 07/2005
4Messenger RNA (mRNA)IBA
04/2015 - 04/2004
3Formaldehyde (Formol)FDA Link
01/2022 - 11/2013
3Deoxyglucose (2 Deoxy D glucose)IBA
10/2021 - 03/2015
3Codon (Codons)IBA
06/2021 - 08/2005
3EpitopesIBA
01/2017 - 09/2003
3Transforming Growth Factor-beta Type II ReceptorIBA
06/2015 - 04/2003
3Epithelial Cell Adhesion MoleculeIBA
06/2012 - 01/2011
3beta CateninIBA
01/2010 - 02/2005
2Glucose (Dextrose)FDA LinkGeneric
10/2021 - 03/2015
2Nonsense Codon (Nonsense Mutation)IBA
07/2020 - 05/2006
2Coloring Agents (Dyes)IBA
01/2020 - 01/2015
2HLA-A Antigens (HLA-A)IBA
01/2020 - 07/2005
2Histocompatibility Antigens Class IIIBA
03/2015 - 08/2010
2LectinsIBA
03/2015 - 03/2005
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2014 - 05/2007
2HLA Antigens (Human Leukocyte Antigens)IBA
09/2010 - 07/2005
2AntibodiesIBA
06/2010 - 10/2009
2WT1 ProteinsIBA
01/2010 - 04/2004
2Complementary DNA (cDNA)IBA
04/2008 - 12/2002
2Polysaccharides (Glycans)IBA
07/2007 - 03/2005
2Monoclonal AntibodiesIBA
07/2005 - 08/2004
2Antineoplastic Agents (Antineoplastics)IBA
06/2003 - 06/2002
1Naproxen (Naprosyn)FDA LinkGeneric
10/2021
1Pharmaceutical PreparationsIBA
10/2021
1CarcinogensIBA
01/2021
1IonsIBA
11/2019
1CarbonIBA
11/2019
1Trans-Activators (Trans-Acting Factor)IBA
01/2018
1DecitabineFDA Link
08/2017
1Peptide Hydrolases (Proteases)FDA Link
01/2017
1Pimozide (Orap)FDA Link
12/2016
1Haloperidol (Haldol)FDA LinkGeneric
12/2016
1Protein Subunit VaccinesIBA
05/2016
1MonosaccharidesIBA
03/2015
1Glycoproteins (Glycoprotein)IBA
03/2015
1AntimetabolitesIBA
03/2015
1Neoplasm Antigens (Tumor Antigens)IBA
03/2015
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2014
1lens epithelium-derived growth factorIBA
03/2014
1Telomerase (Telomerase Reverse Transcriptase)IBA
11/2013
1Viral DNAIBA
09/2013
1Interferon-gamma (Interferon, gamma)IBA
01/2013
1Myristoylated Alanine-Rich C Kinase SubstrateIBA
02/2010
1Staphylococcal Protein A (Protein A)IBA
01/2010
1Arginine (L-Arginine)FDA Link
08/2009

Therapy/Procedure

16Therapeutics
10/2021 - 08/2002
8Drug Therapy (Chemotherapy)
01/2020 - 06/2002
3Immunotherapy
04/2021 - 04/2004
3Ligation
11/2013 - 06/2003
2Hysterectomy
01/2021 - 01/2021
2Salpingo-oophorectomy
01/2021 - 01/2021
2Neoadjuvant Therapy
01/2019 - 09/2003
2Radiotherapy
01/2019 - 06/2003
2Adjuvant Chemotherapy
06/2006 - 09/2005
1Drug Tapering
11/2019
1Chemoprevention
01/2018
1Aftercare (After-Treatment)
01/2013